Okay just thought it was apt to compare Dr. Forbin to Frankenstein. If I remember correctly, the monster kills all of Dr. Frankenstein's (Dr. Forbin's) family/ruins his life (so the world getting nuked) because Dr. Frankenstein wouldn't make him a companion creature (the connection to Guardian?). Frankenstein's main concern was that they would procreate and take over the world (Colossus and Guardian possibly sharing information and ruining both America and the USSR, also the theory of singularity).
This plot point made me HATE the entire book. Since Frankenstein was in charge of making the creature, couldn't he make it sterile? Couldn't we not humanize robots if we're so worried about them learning and taking over, as humans are so inclined to do? I dunno, just a thought.